How to handle groups where clients require a restart from older updates..

Hi,

what is the best way to handle groups with a lot of clients which require a restart from older updates?

Lets say i have still clients that need a reboot from MP4 or older.

How does SEP handle it if i now add a MP5 Package to groups with the clients.

Can this be done or should i move those clients into another group untill they are restartet or can i safely expose those clients to groups with current packages?

Any suggestions?